Nurse Doza’s Podcast comes to life in a very interactive way. Sure you can listen to the podcast, but this is just the beginning of your education in health. Every week, Nurse Doza dives into new health subjects and encourages you to submit your questions to be answered on the podcast, newsletter, YouTube, LinkedIn, and every other way that you like to take in educational media.
Episodes
Monday Oct 02, 2023
What To Do If You’re Always Getting Sick
Monday Oct 02, 2023
Monday Oct 02, 2023
In this episode, Nurse Doza discusses what to do if you're getting sick more than twice a year. He emphasizes that getting sick frequently should not be happening and provide tips and information on how to stay healthy. As the seasons change and fall arrives, it's important to take care of your health and prevent frequent illnesses.
TIMESTAMPS:
00:00 START
04:45 Getting sick more than twice.
07:43 Fast food's impact on digestion.
11:31 Gut health and microbiome.
13:44 Antibiotic resistance.
19:47 Vitamin D and bone health.
21:03 The power of vitamin D.
24:18 Fatty liver and immune system.
28:37 Digestive health and stress.
Are you looking to amplify your body's natural defenses? Dive into our talk today about keeping frequent illnesses at bay and don't miss our mention of Liver Boost – MSW's #1 selling supplement. Enhance your liver's resilience and boost its protective functions.
Click on the link now to discover the benefits of Liver Boost.
https://www.mswnutrition.com/collections/supplements/products/liver-love/?REF=NURSEDOZA
Structured Show Notes
Work on Your Gut
- Immune system’s role in infections¹.
- Gut contains 70–80% of immune cells, highlighting the vital relationship between the gut, microbiota, and immune system¹.
- The gut microbiota, its composition, and how it affects health¹.
- Importance of gut epithelial barrier in protecting against infections¹.
Improve Your Vitamin D Levels
- Immune cells express vitamin D receptor and 1α-hydroxylase¹.
- Connection between vitamin D deficiency and infectious diseases¹.
- Sunlight’s role in vitamin D synthesis¹².
Liver Cleanses
- Liver's position in immune response¹.
- Impact of liver in detecting and clearing pathogens¹.
- Blood supply from gut to liver and its significance².
Stress Relief
- Impact of psychological stress on the immune system¹.
- Acute and chronic stress effects on pro-inflammatory cytokines¹.
- Interaction of stress with immune cells¹.
Change Your Diet
- Relationship between nutrition, gut microbiota, and the immune system¹.
- Effects of Western diet on the immune system³.
- Benefits of probiotics and their impact on health³.
- Potential immunotoxicity of certain pesticides toward immune cells⁵.
Study¹ Study² Study³ Study⁴ Study⁵
With all the insights on boosting your immune system and maintaining optimal health, don't forget the champion of all – your liver! Elevate your health regimen with Liver Boost, MSW's top-tier supplement. Uncover the secret behind its popularity and how it can transform your wellness journey. Ready to experience Liver Boost's magic? Click the link now to place your order.
https://www.mswnutrition.com/collections/supplements/products/liver-love/?REF=NURSEDOZA
Wednesday Sep 27, 2023
Reading Labs: Ferritin - Iron Deficiency, Hair Loss and What You Need to Know”
Wednesday Sep 27, 2023
Wednesday Sep 27, 2023
This episode of Reading Labs discusses the importance of ferritin, which is stored iron in the body. Nurse Doza explains that ferritin is essential for maintaining health and that low levels of ferritin can indicate serious issues, such as iron deficiency. Symptoms of low ferritin may include hair loss. On the other hand, high levels of ferritin can be indicative of infection or cellular damage. He recommends checking ferritin levels regularly and ensuring that ferritin is measured alongside iron levels to assess iron status accurately.
Monday Sep 25, 2023
The Five Things Harming You After Gallbladder Surgery
Monday Sep 25, 2023
Monday Sep 25, 2023
The podcast focuses on the topic of living without a gallbladder and the challenges that can arise after its removal. Nurse Doza empathizes with those who have undergone the surgery and emphasizes the importance of making necessary changes to feel optimized and avoid potential harm.
TIMESTAMPS:
00:00 START
04:50 Importance of post-gallbladder removal diet.
05:01 Dairy and fast food harm gallbladder.
09:47 Gallbladder removal doesn't fix fatty liver.
16:13 Gallbladder removal may cause insulin resistance.
19:23 Digestive issues are interconnected.
24:23 Gallbladder removal can have consequences.
Beforee diving deep into these notes here's a heads-up: If you're searching for the ultimate remedy to support your liver, Liver Boost by MSW is the ticket. Click here to unlock its magic!
1. Gallbladder: What’s its deal?
- Enables fat digestion. So those fries you love? Thank this organ.
- Helps you absorb those fat-soluble superheroes: vitamins A, E, D, and K^1^.
- Assists in escorting out cholesterol and toxins your liver breaks down^1^.
- Fun Fact: Cholecystectomy (fancy term for gallbladder removal) doesn't necessarily relieve abdominal symptoms in all patients. In fact, 40% might still have them post-surgery^1^.
- Another Wow Moment: Approximately 700,000 LCs are done in the US alone^1^. Talk about popularity! It's literally the Beyoncé of surgical procedures worldwide^2^.
Full Study Here^1^ Deep Dive Here^2^
2. The Post-Gallbladder Removal
a) The Dairy and Fast Food Affair: Despite what many think, research suggests a low-fat diet doesn’t necessarily improve symptoms after a gallbladder removal^3^.
b) Your Fatty Liver's SOS: Here's the thing, NAFLD might actually act as an accelerator, pushing gallstone disease to the next level of complications^4^.
c) Insulin Resistance - The Silent Intruder: Several factors within the metabolic syndrome, like insulin resistance, obesity, etc., also hike up the risk of developing cholesterol gallstones^5^.
d) Is Your Gut Leaking? Removing the gallbladder can meddle with the interactions between BAs and intestinal microbiota^6^. Plus, non-biliary diseases might just tag along as free riders^7^.
Digest this info here^6^ More on this^7^
e) Gallbladder's Gone but the Problems Stayed: It's not always rainbows and butterflies after a cholecystectomy. There's a list of possible side-effects: insulin issues, cholesterol woes, increased blood pressure, NASH, IBS, and the dreaded weight gain^8^.
Know what you might be in for^8^
As we wrap this gallbladder journey, remember it's not just about removal, but also about effective aftercare. Boost your liver and ensure it remains your loyal ally with Liver Boost by MSW. Don't let post-cholecystectomy days bring you down; give your body the support it deserves. Purchase your liver's best friend here!
References:
- https://www.hindawi.com/journals/grp/2019/4278373/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118133/
- https://pubmed.ncbi.nlm.nih.gov/31623819/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118133/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118133/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118133/
- https://www.hindawi.com/journals/grp/2019/4278373/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8118133/
Wednesday Sep 20, 2023
Wednesday Sep 20, 2023
In this episode of Reading Labs, the focus is on testosterone and its importance for both men and women. Nurse Doza discusses the different ranges of total testosterone and free testosterone for men, emphasizing the need for routine yearly measurements. Stress and certain factors can suppress testosterone levels in men, so taking action to address these issues is crucial.He also highlights how testosterone replacement therapy can affect natural production. For women, the ranges for total testosterone and free testosterone are significantly lower than those for men. Having too much or too little testosterone can lead to specific health issues, such as PCOS or early menopause. Tune in to learn more about understanding and managing testosterone levels for optimal health.
check out mswnutrition.com/?ref=nursedoza for the best supplements
Monday Sep 18, 2023
Conquering Migraines: Relief and Prevention
Monday Sep 18, 2023
Monday Sep 18, 2023
The main topic of this podcast is migraines and Nurse Doza shares information about their characteristics. He emphasizes that migraines indicate inflammation in the body and should not be normalized as a daily occurrence. Nurse Doza also discusses methods to find relief and prevent migraines in the future, highlighting the significance of addressing the underlying inflammation.
TIMESTAMPS:
00:00 START
04:36 Living with chronic migraines.
09:36 Glutamate and migraines.
12:29 Vitamin B6 and neurotransmitters.
15:30 Liver detox and brain health.
19:19 Low melatonin and migraines.
23:47 Natural pain relievers.
26:09 Migraine treatment with supplements.
30:39 Migraine and stroke risk.
33:18 Underlying issues causing migraines.
36:24 Chronic migraines and natural remedies.
THE D
Before diving into the show notes on migraines, it's important to touch upon a supplement that could play a crucial role in migraine relief - The D.
Have you had your D yet?
It's not just any Vitamin D3 supplement; it's been enhanced with K2 for optimal absorption and efficacy. If you're searching for a potent and high-quality Vitamin D supplement, The D by MSW is your go-to.
Click on the link below to explore more and make a purchase.
https://www.mswnutrition.com/products/the-d/?ref=nursedoza
1. Understanding the Role of Inflammation in Migraines:
Migraines can be an indication of inflammation within the body – signaling that something is not right^(1^).
- Chronic migraine: Defined as a headache occurring on 15+ days in a month for over three months, having migraine features on at least 8 of those days^(1^).
- Migraine & Disability: Ranked second globally as a cause of disability^(1^).
- Glutamate and CNS: Elevated glutamate levels in blood and cerebrospinal fluid of migraine patients hint at its role in migraine pathophysiology^(2^).
- Vitamin B6: Its roles extend beyond being a coenzyme in converting excitatory glutamate into inhibitory GABA; it's also crucial for neurotransmitter production and other neural pathways^(3^).
- NAC and Glutamate: NAC can regulate the glutamatergic system, which is associated with numerous psychiatric disorders^(4^).
Reference 1 | Reference 2 | Reference 3 | Reference 4
2. Identifying Potential Migraine Triggers:
Finding the underlying cause or trigger of your migraine is paramount^(1^). Some probable triggers include:
- Stress (80%)
- Hormonal Changes (65%)
- Skipped Meals (57%) ... and many more listed above.
Additionally, imbalances in melatonin and serotonin levels have been linked to migraines^(2^,3^).
Reference 1 | Reference 2 | Reference 3
3. Natural Pain Relievers for Migraine Management:
Several natural treatments, like turmeric, fish oil, vitamin B2, magnesium, and butterbur, may aid in providing relief^(1^).
- Vitamin D: Supplementation can reduce the frequency of attacks in migraine sufferers^(4^,5^).
- Serotonin (5-HT): Implicated in migraine due to its vasoconstrictor effects and presence in pain-related regions^(3^).
- Melatonin: Demonstrates potential analgesic effects in various conditions, including migraines^(3^).
Reference 1 | Reference 3 | Reference 4 | Reference 5
4. Chiropractic Treatments for Migraines:
Studies suggest that chiropractic spinal manipulative therapy (CSMT) may be an effective treatment for migraines^(1^).
5. Migraines & Stroke Risks:
People with migraine auras have a slightly heightened risk of stroke^(1^). Consistent associations have been made between migraines with aura and increased risk of ischemic stroke^(2^).
As we conclude today's discussion, let's not forget the potential role of Vitamin D3 in migraine management. Once again, for those who are keen on exploring a top-notch Vitamin D3 supplement enriched with K2, consider giving The D by MSW a shot. It's formulated for those who settle for nothing but the best.
Click the link below to secure your bottle today. Make the right choice for your health!
https://www.mswnutrition.com/products/the-d/?ref=nursedoza
Disclaimer: Always consult with a healthcare professional before starting any supplement or making significant changes to your health routine.
Wednesday Sep 13, 2023
Reading Labs: GGT - A Key Marker for Liver Health and Antioxidant Production”
Wednesday Sep 13, 2023
Wednesday Sep 13, 2023
This podcast episode discusses the importance of the GGT liver enzyme test in determining the presence of fatty liver disease. Nurse Doza explains that GGT levels above 30 may indicate liver inflammation and damage. However, he emphasizes that GGT alone is not sufficient to assess liver health and advises combining it with other tests like AST and ALT, as well as an ultrasound. Nurse Doza encourages listeners to take control of their health and request the GGT test if necessary.
For the best supplements, check out mswnutrition.com/?ref=nursedoza
Monday Sep 11, 2023
Reduce Bloating: 5 Tips for a Healthy Gut and Better Digestion
Monday Sep 11, 2023
Monday Sep 11, 2023
In this episode, Nurse Doza discusses the topic of bloating and provides tips on how to reduce it. Bloating is a common issue, with nearly 40% of the general population reporting experiencing it. Nurse Doza encourages listeners to take note of their own symptoms and do their own research to find strategies that work for them. This episode aims to empower listeners to take action and find relief from bloating.
00:00 START
02:29 Tips to reducing bloat.
07:40 Elimination diet and bloating.
10:38 Gut and brain interaction.
13:52 L-glutamine supplementation and gut health.
17:48 Support your liver.
21:10 Supporting the liver
23:41 Depression and Serotonin Production.
28:08 Digestive issues and processed foods.
30:39 Serotonin and mood support.
Elevate your mood naturally with Bliss. Our carefully formulated supplement is designed to support neurotransmitter production, ensuring a balanced and joyful life. Before diving into the episode, don’t forget to click the link and explore how Bliss can transform your everyday experiences.
https://www.mswnutrition.com/products/bliss/?ref=nursedoza
1. Diet and Bloating
-
Examine your diet to identify potential causes of bloat.
-
Low Fermentable Oligo-, Di- and Mono-saccharides And Polyols (FODMAP) Diet is highly recommended for treating IBS symptoms¹.
-
IBS diagnosis is based on the Rome IV criteria, highlighting the relation of abdominal pain with defecation and changes in bowel habits¹.
-
A significant percentage of IBS patients, especially women, associate their symptoms with food intake. Bloating and abdominal pain are the most frequent complaints¹.
-
Commonly reported dietary triggers include carbohydrates, fatty foods, coffee, alcohol, and hot spices¹.
-
Gluten can disrupt bowel barrier functions, especially in certain patients akin to celiac individuals¹.
-
Excessive fructose intake exacerbates NAFLD markers² and can disturb the intestinal barrier, intensifying liver inflammation and fructose conversion into fatty deposits³.
2. Gut Health and Bloating
-
Address gut health to alleviate bloating.
-
DGBIs encompass conditions like IBS, reflux hypersensitivity, and functional dyspepsia⁴.
-
Several factors, including past infections and psychological conditions, can lead to DGBIs⁴.
-
Disorders of gut–brain interaction or FGIDs are recognized as microbiota–gut–brain abnormalities prevalent worldwide⁵.
-
Gut microbiota is susceptible to changes due to varying factors like diet and psychological state⁵.
-
Methanogenic microbes in the colon can lead to slowed gut transit and constipation due to serotonin depletion⁵.
3. Bloodwork and Bloating
-
Seek bloodwork to identify underlying causes.
-
hs-CRP is linked with NAFLD⁶.
-
IBS has been found to predict higher hs-CRP levels⁷.
-
Elevated ALT is often observed in IBS patients⁸.
-
Excessive gas correlates significantly with liver steatosis and heightened ALT levels⁹.
4. Liver Health and Bloating
-
Support the liver for better digestion.
-
IBS symptoms like abdominal pain and bloating can also indicate NAFLD¹⁰.
-
Cholecystitis can lead to abdominal bloating¹¹.
-
The gallbladder isn't essential for a healthy life¹¹.
5. Mood, Serotonin, and Bloating
-
Maintain a balanced mood and serotonin levels to manage bloating.
-
Serotonin has diverse intestinal functions¹².
-
IBS might be associated with serotonin dysfunction affecting gut motility¹².
-
Changes in serotonin levels can be addressed with specific medications for symptom relief¹³.
-
Essential components for serotonin synthesis include tetrahydrobiopterin (BH4) and pyridoxine (vitamin B6)¹⁴.
As you've learned today, neurotransmitter balance plays a crucial role in our overall well-being. Why not support your body's natural balance with Bliss? Click on the link to discover how this transformative supplement can amplify your health journey.
https://www.mswnutrition.com/products/bliss/?ref=nursedoza
Wednesday Sep 06, 2023
Reading Labs: Cortisol - Balancing Stress and Sleep
Wednesday Sep 06, 2023
Wednesday Sep 06, 2023
In this episode of Reading Labs, Nurse Doza discusses cortisol, a hormone produced by the body in response to stress. Cortisol not only acts as a stress response, but it also increases blood sugar levels to provide energy throughout the day. The optimal range for cortisol levels varies throughout the day, with higher levels in the morning and lower levels in the evening. If cortisol levels are imbalanced, it can affect sleep and lead to difficulties falling asleep. Checking cortisol levels can help identify any adrenal issues and guide individuals towards achieving a healthier balance.
Monday Sep 04, 2023
5 Liver-Supporting Practices for a Healthier You
Monday Sep 04, 2023
Monday Sep 04, 2023
The topic of this podcast episode is the liver and its importance for bodily function. Nurse Doza emphasizes how common it is for people to have a fatty liver due to their diet, specifically fast food consumption. He explains how the sugar and fructose in these foods directly affect the liver and contribute to non-alcoholic fatty liver disease. He also encourages listeners to take control of their diet and make choices that support a healthy liver. This episode provides practical tips for improving liver health and acknowledges the positive impact the podcast is having on listeners' lives.
- TIMESTAMPS:
- 00:00 START
- 06:20 The liver and its importance.
- 09:07 Non-alcoholic fatty liver disease.
- 12:09 Importance of food and nutrients.
- 15:44 Alcohol's contribution to diabetes.
- 21:46 Liver-supporting supplements.
- 23:05 Resveratrol in the Mediterranean diet.
- 29:38 Liver health and supplements.
- 32:45 Gut and liver relationship.
- 34:07 Fasting for a healthier liver.
- 37:22 Liver health practices.
Introducing Liver Love: Every vibrant life begins with a healthy core. Cleanse, rejuvenate, and love your liver with our premium supplement, "Liver Love". Designed meticulously for Phase 1 and 2 of liver detoxing. Begin your journey to a healthier you. Click here to get Liver Love now!
Show Notes:
- The Importance of Supporting Antioxidant Production.[^1^]
- The crux of health issues: Inflammation.
- The origin of inflammation: Stress.
- Consequences of chronic stress: Bodily dysfunction.
- The liver: A powerhouse of antioxidant production[^2^].
- Glutathione: Liver's potent gift and its profound benefits[^3^].
- Introducing NAC: Glutathione's precursor and its significance[^4^].
- The need for NAC and glutathione supplementation.
- The liver-enhancing power of B vitamins[^5^].
- Hormone Regulation & The Liver[^6^]
- The liver's pivotal role in hormone regulation.
- The communicative power of hormones.
- Liver: The body's natural storage facility.
- Better hormones equate to a healthier liver[^7^].
- Early menopause's potential link to liver health[^8^].
- The underappreciated link: Liver and insulin.
- The domino effect: Insulin issues leading to hormonal imbalances[^9^].
- The Perils of Fast Food on Liver Health[^10^]
- The challenges in processing fast food.
- Residues of past unhealthy diets lingering in the liver.
- Beyond fast food: The toll of an unhealthy diet on the liver[^11^].
- The equation of good fats and a healthier liver.
- Avocado: The liver's best friend.
- Monounsaturated fat: A top-tier dietary inclusion[^12^].
- The liver's role in cholesterol production[^13^].
- The promise of fish oil for liver wellness[^14^].
- The connection: Fatty liver, omega 3, and choline deficiencies[^15^].
- Decoding the Relationship: Liver & Estrogen[^16^]
- Fatty liver's association with compromised estrogen.
- Estrogen production's direct tie to the liver[^17^].
- The toll of birth control on liver health and estrogen quality[^18^].
- The malleability of epigenetics[^19^].
- Stress, liver health, and its implications on estrogen[^20^].
- The genetic connection to liver health and detoxification needs[^21^].
- Delving into the COMT gene's role in hormone regulation[^22^].
- The intersection of cholesterol, liver, and menopause-associated estrogen[^23^].
- Methylation & Its Influence on Liver Function[^24^]
- The expression of the MTHFR gene in the liver.
- Prevalence and implications of MTHFR gene mutation[^25^].
- The methylation cycle's role in vitamin metabolism[^26^].
- Significance of B9 in methylation and liver functions[^27^].
- The interconnected web: MTHFR gene's impact on various bodily processes[^28^].
- Glutathione production's link to correct methylation[^29^].
- Methylation's role in disease risk[^30^].
- The importance of methylated vitamins for MTHFR gene support[^31^].
- The intertwined roles of MTHFR and COMT genes in methylation[^32^].
Discover Liver Love: Let's face it, our livers undergo a lot, daily. Toxins, processed foods, medications, and more. It's time to give back. Show your liver some love with our specially formulated detox supplement, "Liver Love". The first step towards a healthier tomorrow starts with a cleanse today. Tap here to give your liver the love it deserves!
---
**REFERENCES**:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320789/figure/molecules-23-03305-f001/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/#B4
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8125908/
- https://pubmed.ncbi.nlm.nih.gov/14973104/
- https://pubmed.ncbi.nlm.nih.gov/19095062/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726297/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637678/
- https://pubmed.ncbi.nlm.nih.gov/334126/
- https://www.ahajournals.org/doi/10.1161/JAHA.120.020560
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228367/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123374/#MOESM3
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674329/#R28
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7531579/#B30
Wednesday Aug 30, 2023
IN CASE YOU MISSED IT! How to Lose Weight When You Are Insulin Resistant
Wednesday Aug 30, 2023
Wednesday Aug 30, 2023
In this Re Release of Episode 10 on 5/10/23 of the School of Doza podcast, Nurse Doza discusses how to lose weight when you are insulin resistant. He starts by emphasizing the commitment needed to make these changes and encourages listeners to sign up for the newsletter on Nursedoza.com for weekly content and advice. Nurse Doza then explains that insulin resistance is common and leads to inflammation, and provides specific changes that can help with weight loss.
TIMESTAMPS:
00:00 Start
02:25 Insulin resistance and weight gain.
04:21 Insulin Resistance and Diabetes.
08:02 Leptin Resistance and Weight Loss.
11:50 Brown fat and weight loss.
19:42 Insulin resistance and weight loss.
24:29 Activation of parasympathetic nervous system.
27:23 Insulin Resistance and Weight Loss.
31:57 Resveratrol supplement.
Increase your energy levels and support your metabolism with Mitochondriac! Get 10% off when you use code NURSEDOZA at checkout. Visit the link to learn more and start feeling your best today!
https://www.mswnutrition.com/mitochondriac
REFERENCES:
What being insulin resistant means: _inflammation
your body is reluctant to release anymore insulin___ (1)
“Insulin resistance is identified as an impaired biologic response to insulin stimulation of target tissues, primarily the liver, muscle, and adipose tissue” (2)
“You do not have to be overweight to have insulin resistance” (1)
“The spectrum of disease associated with insulin resistance includes obesity, cardiovascular disease, nonalcoholic fatty liver disease, metabolic syndrome, and polycystic ovary syndrome(PCOS).” (2)
Ways to measure IR: “HOMA-IR, serum triglyceride, and triglyceride/HDL ratio.” (2)
**“Insulin resistance is thought to precede the development of T2DM by 10 to 15 years. “ (2)
“While no medications are FDA approved for the treatment of insulin resistance” (3)
“Lifestyle modification should be the primary focus for the treatment of insulin resistance.” (3)
References: https://www.cdc.gov/diabetes/basics/insulin-resistance.html (1)
https://www.ncbi.nlm.nih.gov/books/NBK507839/ (2)
IR: https://www.ncbi.nlm.nih.gov/books/NBK507839/ (3)
Leptin: “Leptin resistance is defined by a reduced sensitivity or a failure in response of the brain to leptin, showing a decrease in the ability of leptin to suppress appetite or enhance energy expenditure, which causes an increased food intake and finally leads to overweight, obesity, cardiovascular diseases, and other metabolic disorders” (1)
“A minor increase in leptin concentration reduces the appetite and leads to a decrease in body weight;3 however, in obesity, despite increased leptin concentration, the efficacy of the anorexic effect of leptin is decreased,1,3 with leptin resistance developing due to a defect in intracellular signaling associated with the leptin receptor or decreases in leptin transport across the blood–brain barrier (BBB)” (2)
“participation of leptin in the development of cardiovascular and autoimmune diseases and cancer” (2)
References: leptin: https://pubmed.ncbi.nlm.nih.gov/30390289/ (1)
Leptin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354688/ (2)
IR: https://www.ncbi.nlm.nih.gov/books/NBK507839/ (3)
References: leptin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354688/ (1)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815269/ (2)
https://academic.oup.com/jcem/article/91/12/4753/2656230?login=false (3)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848049/ (4)
References: https://www.diabetes.co.uk/insulin/insulin-sensitivity.html (1)
https://www.ncbi.nlm.nih.gov/books/NBK507839/ (2)
Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action https://pubmed.ncbi.nlm.nih.gov/28704113/ (3)
Effects of resveratrol therapy on glucose metabolism, insulin resistance, inflammation, and renal function in the elderly patients with type 2 diabetes mellitus: A randomized controlled clinical trial protocol https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371579/ (4)
https://academic.oup.com/jcem/article/91/12/4753/2656230?login=false (5)
References: The Role of Insulin Resistance in Nonalcoholic Fatty Liver Disease https://academic.oup.com/jcem/article/91/12/4753/2656230?login=false (1)
https://www.pnas.org/doi/10.1073/pnas.2007856117 (2)
“In people with diabetes and pre-diabetes, increasing levels of HbA1c and age may be main factors related to impaired parasympathetic function” (1)
“Depression has been associated with both increased insulin resistance and reduced heart rate variability (HRV), the latter being an indicator of low parasympathetic drive” (2)
References: https://www.nature.com/articles/s41598-022-22675-2 (1)