Nurse Doza’s Podcast comes to life in a very interactive way. Sure you can listen to the podcast, but this is just the beginning of your education in health. Every week, Nurse Doza dives into new health subjects and encourages you to submit your questions to be answered on the podcast, newsletter, YouTube, LinkedIn, and every other way that you like to take in educational media.
Episodes
Friday May 15, 2026
Friday May 15, 2026
What if a single gene is quietly affecting your mood, energy, sleep, and focus — and most doctors never test for it? In this episode of the Longevity Series, Nurse Doza breaks down MTHFR gene support: what methylation is, why this gene matters, and how BLISS by MSW Nutrition delivers targeted sublingual support — sometimes with noticeable results the same day.
BLISS by MSW Nutrition is a sublingual powder formulated with two active ingredients specifically designed to support the MTHFR gene and the methylation cycle. For people with MTHFR variants — who may struggle with mood regulation, low energy, brain fog, and disrupted sleep — BLISS bypasses the digestive process entirely, delivering its active compounds directly into the bloodstream under the tongue for fast, efficient absorption. Nurse Doza and co-founder Baldo both have confirmed MTHFR issues and take BLISS daily — this is a supplement built from personal need, not theory. One box contains 30 packets, making it a full 30-day protocol.
👉 Try BLISS with code BLISSMAY at: https://bliss.mswnutrition.com
5 Key Takeaways
MTHFR gene variants are far more common than most people realize. Approximately 30–40% of people carry a variant of the MTHFR gene that reduces enzyme efficiency — sometimes by as much as 70%. If you’ve ever been dismissed with “normal” labs while still feeling off, this gene may be the missing piece.
Methylation controls more of your health than you think. The methylation cycle governs neurotransmitter production, detoxification, hormone regulation, and DNA repair. When MTHFR impairs this pathway, mood, energy, digestion, and long-term health can all be affected.
Low serotonin from poor methylation can wreck your sleep. Because serotonin is the precursor to melatonin, impaired methylation can directly disrupt your sleep-wake cycle. Supporting the MTHFR pathway can help restore the serotonin–melatonin conversion your body needs for deep, restorative sleep.
Sublingual delivery changes the absorption game. Traditional capsules and powders can lose significant potency through first-pass digestion. BLISS is a sublingual powder that bypasses the GI tract entirely, entering the bloodstream directly through the oral mucosa for faster, more efficient delivery.
You can override poor genetics with the right support. Having an MTHFR variant is not a life sentence. Targeted methylation support through active-form nutrients can help compensate for reduced enzyme activity, improving neurotransmitter output and overall cellular function.
Resources
“Methylenetetrahydrofolate Reductase and Psychiatric Diseases” — PMC, NCBI
Peer-reviewed research examining how MTHFR gene mutations affect one-carbon metabolism and their established link to psychiatric disorders, mood regulation, and neurotransmitter synthesis including serotonin and dopamine. https://pmc.ncbi.nlm.nih.gov/articles/PMC6218441/
“Discovery of MTHFR Deficiency in Individuals With Common Psychiatric Comorbidities” — PMC, NCBI
Retrospective case review from PMC establishing the connection between MTHFR deficiency and common psychiatric presentations, with focus on neurotransmitter pathways including serotonin, norepinephrine, and dopamine. https://pmc.ncbi.nlm.nih.gov/articles/PMC11088868/
“Chronic Insomnia in the Setting of MTHFR Polymorphism” — Journal of Clinical Sleep Medicine, PMC
Published case study documenting treatment-resistant chronic insomnia successfully resolved by targeting MTHFR polymorphism, demonstrating the serotonin–melatonin–sleep connection and the role of methylation support in restoring sleep quality. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974368/
“Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive” — PMC, NCBI
Comprehensive review of sublingual and buccal delivery mechanisms, demonstrating how this route bypasses first-pass hepatic metabolism and leverages the oral mucosa’s rich vascular network for faster, more efficient systemic absorption versus standard oral supplementation. https://pmc.ncbi.nlm.nih.gov/articles/PMC12389210/
“The MTHFR Gene Mutation and Its Connection to Mental Health” — Genomind
Evidence-based overview of how MTHFR gene variants reduce the body’s ability to convert vitamin B9 into active methylfolate, directly impacting neurotransmitter synthesis and predisposing individuals to low mood, low energy, and cognitive difficulties. https://genomind.com/patients/mthfr-and-the-role-it-plays-in-your-mental-health/
Connect with Nurse Doza
🔗 JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
• YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
• Instagram: https://www.instagram.com/nursedoza/
• Website: http://www.nursedoza.com/
• LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
• TikTok: https://www.tiktok.com/@nursedoza
• Twitter: https://twitter.com/nursedoza
Monday May 11, 2026
Monday May 11, 2026
Chronic stress belly fat is more than a feeling — it changes your hormones, metabolism, and cravings. Nurse Doza breaks down 5 specific mechanisms — cortisol, insulin resistance, leptin dysfunction, fatty liver, and late-night eating — explaining exactly why belly fat won't budge and what to do about it.
FEATURED PRODUCT:
The Metabolic Pack from MSW Nutrition is the complete protocol for everything covered in this episode. Liver Boost combines turmeric (curcumin), green tea extract (EGCG), NAC, and alpha-lipoic acid to reduce inflammation, support liver detoxification, and combat insulin resistance at the cellular level. Mitochondriac delivers resveratrol and key mitochondrial support to activate AMPK, improve cellular energy, and lower inflammatory markers linked to chronic stress and weight gain. Zen contains an adaptogenic blend with Rhodiola, Ginseng, Eleuthero, Schisandra, and bovine adrenal glandular support — specifically designed to regulate cortisol and protect adrenal health. Together, these three supplements form a 60–90 day metabolic reset built to address the root causes of chronic stress belly fat.
👉 Get the Metabolic Pack here: https://mswnutrition.com/collections/bundles/products/metabolic-pack
JOIN THE SCHOOL OF DOZA
Still trying to figure out why the belly fat won't budge despite doing everything right? You're not alone — and generic advice isn't enough. Inside the School of Doza, you'll find a community of people working through the same hormonal, metabolic, and stress-related challenges covered in this episode. Every Wednesday, Nurse Doza hosts a live Ask Me Anything that works exactly like a group consult — bring your cortisol questions, your labs, your weight loss frustrations, and get real answers. Your first 7 days are completely free.
👉 Start your free trial: https://community.schoolofdoza.com/c/start-here
5 KEY TAKEAWAYS
Cortisol is not the villain — it's essential.
Insulin resistance is the engine behind belly fat
You may be eating when you are not actually hungry.
Fatty liver and belly fat are directly connected.
When you eat matters as much as what you eat.
TIMESTAMPS
00:00 – START
01:03 – The connection between chronic stress, cortisol, and belly fat
03:30 – Why cortisol is not the villain
05:00 – Cortisol — how chronic elevation drives fat storage
06:00 – Insulin resistance — the real driver of weight gain
07:25 – Ozempic, GLP-1 agonists, and why they don't fix the root cause
09:53 – Natural compounds for insulin resistance: berberine, curcumin, EGCG, resveratrol
16:43 – Leptin resistance — eating when you are not actually hungry
21:00 – Fasting as the most sustainable tool for lowering leptin and insulin
23:51 –Fatty liver — the overlooked driver of belly fat
26:42 – The global obesity crisis and the limits of pharmaceutical solutions
28:50 – Eating late at night disrupts melatonin and glucose tolerance
RESOURCES
1. Cortisol and Weight Gain (HPA Axis and Obesity Review) — https://pmc.ncbi.nlm.nih.gov/articles/PMC9285588/
2. Visceral Adipose Tissue, 11β-HSD1, and Metabolic Syndrome https://pmc.ncbi.nlm.nih.gov/articles/PMC4517681/
3. Natural Polyphenols and Obesity-Induced Insulin Resistance https://pmc.ncbi.nlm.nih.gov/articles/PMC12872655/
4. Leptin, Leptin Resistance, and Obesity https://pmc.ncbi.nlm.nih.gov/articles/PMC8167040/
5. Fatty Liver (NAFLD) and Obesity https://pmc.ncbi.nlm.nih.gov/articles/PMC3575093/
6. Nighttime Eating and Weight Gain https://pmc.ncbi.nlm.nih.gov/articles/PMC6322536/
7. Nighttime Macronutrient Intake and Insulin Resistance https://pmc.ncbi.nlm.nih.gov/articles/PMC4425165/
8. Meal Timing, Late Dinner, and Weight Loss Difficulty https://pmc.ncbi.nlm.nih.gov/articles/PMC6893547/
9. Hume Health BodyPod — At-Home Body Composition Measurement (use code NURSEDOZA) https://humehealth.com
CONNECT
🔗 Connect with Nurse Doza:
JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza
Friday May 08, 2026
Friday May 08, 2026
Chronic stress belly fat is more than a feeling — it changes your hormones, metabolism, and cravings. Nurse Doza breaks down 5 specific mechanisms — cortisol, insulin resistance, leptin dysfunction, fatty liver, and late-night eating — explaining exactly why belly fat won't budge and what to do about it.
FEATURED PRODUCT:
The Metabolic Pack from MSW Nutrition is the complete protocol for everything covered in this episode. Liver Boost combines turmeric (curcumin), green tea extract (EGCG), NAC, and alpha-lipoic acid to reduce inflammation, support liver detoxification, and combat insulin resistance at the cellular level. Mitochondriac delivers resveratrol and key mitochondrial support to activate AMPK, improve cellular energy, and lower inflammatory markers linked to chronic stress and weight gain. Zen contains an adaptogenic blend with Rhodiola, Ginseng, Eleuthero, Schisandra, and bovine adrenal glandular support — specifically designed to regulate cortisol and protect adrenal health. Together, these three supplements form a 60–90 day metabolic reset built to address the root causes of chronic stress belly fat.
👉 Get the Metabolic Pack here: https://mswnutrition.com/collections/bundles/products/metabolic-pack
JOIN THE SCHOOL OF DOZA
Still trying to figure out why the belly fat won't budge despite doing everything right? You're not alone — and generic advice isn't enough. Inside the School of Doza, you'll find a community of people working through the same hormonal, metabolic, and stress-related challenges covered in this episode. Every Wednesday, Nurse Doza hosts a live Ask Me Anything that works exactly like a group consult — bring your cortisol questions, your labs, your weight loss frustrations, and get real answers. Your first 7 days are completely free.
👉 Start your free trial: https://community.schoolofdoza.com/c/start-here
5 KEY TAKEAWAYS
Cortisol is not the villain — it's essential.
Insulin resistance is the engine behind belly fat
You may be eating when you are not actually hungry.
Fatty liver and belly fat are directly connected.
When you eat matters as much as what you eat.
TIMESTAMPS
00:00 – START
01:03 – The connection between chronic stress, cortisol, and belly fat
03:30 – Why cortisol is not the villain
05:00 – Cortisol — how chronic elevation drives fat storage
06:00 – Insulin resistance — the real driver of weight gain
07:25 – Ozempic, GLP-1 agonists, and why they don't fix the root cause
09:53 – Natural compounds for insulin resistance: berberine, curcumin, EGCG, resveratrol
16:43 – Leptin resistance — eating when you are not actually hungry
21:00 – Fasting as the most sustainable tool for lowering leptin and insulin
23:51 –Fatty liver — the overlooked driver of belly fat
26:42 – The global obesity crisis and the limits of pharmaceutical solutions
28:50 – Eating late at night disrupts melatonin and glucose tolerance
RESOURCES
1. Cortisol and Weight Gain (HPA Axis and Obesity Review) — https://pmc.ncbi.nlm.nih.gov/articles/PMC9285588/
2. Visceral Adipose Tissue, 11β-HSD1, and Metabolic Syndrome https://pmc.ncbi.nlm.nih.gov/articles/PMC4517681/
3. Natural Polyphenols and Obesity-Induced Insulin Resistance https://pmc.ncbi.nlm.nih.gov/articles/PMC12872655/
4. Leptin, Leptin Resistance, and Obesity https://pmc.ncbi.nlm.nih.gov/articles/PMC8167040/
5. Fatty Liver (NAFLD) and Obesity https://pmc.ncbi.nlm.nih.gov/articles/PMC3575093/
6. Nighttime Eating and Weight Gain https://pmc.ncbi.nlm.nih.gov/articles/PMC6322536/
7. Nighttime Macronutrient Intake and Insulin Resistance https://pmc.ncbi.nlm.nih.gov/articles/PMC4425165/
8. Meal Timing, Late Dinner, and Weight Loss Difficulty https://pmc.ncbi.nlm.nih.gov/articles/PMC6893547/
9. Hume Health BodyPod — At-Home Body Composition Measurement (use code NURSEDOZA) https://humehealth.com
CONNECT
🔗 Connect with Nurse Doza:
JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza
Monday May 04, 2026
Monday May 04, 2026
Sleep and weight gain are directly connected. Poor sleep disrupts hormones, raises blood sugar, tanks testosterone and estrogen, causes fatty liver, and wrecks your gut. If you've been doing everything right and the scale won't move, your sleep could be the missing link.
FEATURED PRODUCT
Chill by MSW Nutrition is a powdered drink mix formulated to support your body's natural calming chemistry — exactly what's needed when chronic stress and cortisol overload are stealing your sleep. Featuring GABA, L-Theanine, myo-Inositol, Taurine, and Magnesium, Chill helps balance neurotransmitters, quiet the nervous system, and promote the deep, restorative sleep your hormones, metabolism, and weight depend on — all five mechanisms discussed in this episode.
👉 Get Chill here: https://mswnutrition.com/products/chill
5 KEY TAKEAWAYS
Sleep deprivation activates the HPA axis, raising cortisol and suppressing melatonin
Poor sleep spikes blood sugar and insulin even without eating.
Lack of REM sleep directly lowers testosterone in men and disrupts estrogen in women.
Poor sleep causes fatty liver (MASLD/NAFLD) by disrupting insulin sensitivity, lipid metabolism, and inflammation markers like TNF-alpha, IL-6, and CRP. Melatonin — made during quality sleep — has been shown to actually prevent and reverse fatty liver progression.
Sleep deprivation damages the gut microbiome by reducing beneficial bacteria like Akkermansia and Bacteroides, breaking down the intestinal barrier, and triggering gut-brain neuroinflammation — all of which contribute to weight gain and metabolic dysfunction.
TIMESTAMPS
00:00 START – Welcome and episode overview
00:30 – Opening hook: why sleep is the missing weight loss variable
01:45 – How sleep deprivation disrupts hormones, metabolism, and fat storage
03:30 – School of Doza: Wednesday AMAs and free 7-day trial
06:40 – Way 1: Poor sleep increases inflammation via cortisol and HPA axis activation
10:30 – The cortisol-melatonin connection and why melatonin matters for weight
13:00 – Melatonin in the gut: 10–100x more than the brain, and what that means
15:30 – Way 2: Poor sleep causes high blood sugar and insulin resistance
17:40 – Late-night eating, sugar crashes, and the 3 a.m. wake-up pattern
21:00 – Leptin disruption, nighttime hunger, and the diabetes–sleep link
25:30 – Amyloid, insulin, and the Alzheimer's connection to sleep deprivation
29:30 – Way 3: Poor sleep lowers testosterone and estrogen
31:30 – Estrogen's role in initiating sleep; menopause, CPAP, and beer belly
32:00 – Way 4: Poor sleep causes fatty liver (MASLD/NAFLD)
35:30 – Way 5: Poor sleep destroys gut health and microbiome diversity
37:00 – Chill by MSW Nutrition: the sleep and cortisol support product
38:30 – Closing thoughts and call to join the School of Doza
RESOURCES
Sleep Disorders and Metabolic-Associated Steatotic Liver Disease (MASLD) – Covers HPA axis activation, melatonin's role in fatty liver, estrogen/testosterone disruption, and insulin sensitivity. https://pmc.ncbi.nlm.nih.gov/articles/PMC12315459/
Sleep Duration, Type 2 Diabetes, and Glucose Metabolism – Documents the relationship between short sleep duration and elevated T2DM risk, and the role of NF-kB inflammatory markers. https://pmc.ncbi.nlm.nih.gov/articles/PMC6893547/
Sleep Deprivation, Gut Microbiota Dysbiosis, and Metabolic Disease – Covers leptin/ghrelin shifts, serum amyloid A, Firmicutes/Bacteroidetes ratio changes, and intestinal barrier disruption. https://pmc.ncbi.nlm.nih.gov/articles/PMC10253795/
Chill by MSW Nutrition – GABA, L-Theanine, Magnesium, myo-Inositol, and Taurine sleep and cortisol support blend. https://mswnutrition.com/products/chill
School of Doza Community – Join for free sleep classes, Wednesday AMAs, and group coaching. https://community.schoolofdoza.com/c/start-here
🔗 Connect with Nurse Doza:
JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza
Thursday Apr 30, 2026
Thursday Apr 30, 2026
Two supplements. One morning stack. Nurse Doza breaks down why Liver Boost and Berberine Plus work better together — and how the Good Poops Protocol combines them with a gut-repair formula to support liver, gallbladder, blood sugar, and weight.
Today is the last day to save an extra 10% automatically on the full protocol.
The Good Poops Protocol is a three-supplement system designed by Nurse Doza, DC, RN, FNP-C — combining Liver Boost (16-ingredient Phase I + II liver detox support), Berberine Plus (5x more bioavailable dihydroberberine for blood sugar and digestion), and Gut (L-Glutamine formula for intestinal lining and gut flora) — into one 60-day protocol. As discussed in this episode, when you support liver function and blood sugar management simultaneously, the downstream effects on digestion, weight, and overall health can be profound — and noticeable within days.
👉 Get the Good Poops Protocol
Extra 10% Off Today: https://good-poops.mswnutrition.com/
(Discount is automatic — no code needed — April only, last day)
5 Key Takeaways
Liver Boost and Berberine work better together. Taking them separately misses the synergy. Stacked together first thing in the morning on an empty stomach, they hit liver detoxification and blood sugar management simultaneously — two systems that are deeply interconnected.
Your blood sugar ends up in your liver. Every glucose spike you take in gets processed by the liver. If liver function is compromised, blood sugar regulation suffers. Supporting both at once is the smarter approach.
Timing and dosing matter. Start with one to two Liver Boost capsules in the morning on an empty stomach. Add Berberine Plus at the same time, or experiment with a dose before your largest meal. Most people notice digestive changes within days, and broader improvements within a few weeks.
The Good Poops Protocol adds the gut layer. Liver Boost and Berberine address upstream function, but the Gut formula — an L-Glutamine-based powder — repairs the intestinal lining and supports gut flora. All three systems depend on each other.
Play around with it. There's no single rigid protocol. Nurse Doza encourages listeners to experiment with meal timing, split dosing, and combinations to find what works for their specific body and goals.
Resources
"Biochemical Changes Associated with Non-Alcoholic Fatty Liver Disease in Response to Berberine Treatment" — Systematic review and meta-analysis from Frontiers in Pharmacology demonstrating that berberine significantly reduced fasting blood glucose levels and improved liver enzyme markers (ALT, AST) across both clinical and preclinical studies.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433188/
"Efficacy and Safety of Berberine Alone for Several Metabolic Disorders" — PMC systematic review and meta-analysis of randomized clinical trials examining berberine's effects on NAFLD, type 2 diabetes, blood sugar, and lipid profiles.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8107691/
"Berberine Influences Multiple Diseases by Modifying Gut Microbiota" — Frontiers in Nutrition 2023 review covering how berberine's interaction with gut microbiota produces downstream effects on metabolic disease, liver disease, and intestinal health.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435753/
"Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review" — PMC review of 29 randomized controlled trials (3,846 participants) evaluating silymarin's hepatoprotective effects and impact on liver enzyme levels across diverse clinical conditions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667129/
"Regulation of Hepatic Glucose Metabolism in Health and Disease" — Nature Reviews Endocrinology / PMC explaining the liver's central role in glucose homeostasis, including how hepatic dysfunction contributes to hyperglycemia in type 1 and type 2 diabetes.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5777172/
Connect with Nurse Doza
🔗 JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza
Thursday Apr 23, 2026
Thursday Apr 23, 2026
In this Supplement Ingredient Series episode, Nurse Doza breaks down glutathione — the master antioxidant your liver makes to fight inflammation, detox your body, and protect your brain. With roughly 1 in 4 people worldwide carrying a fatty liver, most are running on low reserves. Learn why glutathione is non-negotiable for energy, performance, and recovery — plus how to get your own vial to use at home.
Featured Partner: SHED
SHED delivers practitioner-grade glutathione in a vial you can use at home — the same master antioxidant Nurse Doza has administered through thousands of injections and IVs in clinical practice. Because the liver's ability to produce glutathione drops when it's fatty, inflamed, or overworked, supplementing directly is often the fastest way to restore energy, mental clarity, and detoxification pathways — exactly the mechanism discussed in this episode.
👉 Get your SHED glutathione vial here: https://tryshed.com
👉 Use code DOZA30 at: https://tryshed.com
5 Key Takeaways
Glutathione is your body's master antioxidant. It's a tripeptide made in the liver that neutralizes free radicals, recycles other antioxidants like vitamin C and E, and powers detoxification pathways throughout the body.
Your liver is the glutathione factory. Peer-reviewed research confirms the liver is the central hub for glutathione production and systemic distribution — when hepatic function drops, so does your antioxidant defense system.
Fatty liver compromises antioxidant production. Global NAFLD prevalence estimates range from roughly 25–32% of adults, meaning a significant portion of the population has reduced capacity to make glutathione — which is exactly when fatigue, brain fog, and chronic inflammation start showing up.
Oral glutathione has poor bioavailability. Because glutathione is broken down by enzymes in the digestive tract, injections and IVs bypass digestion and deliver the molecule directly into circulation — which is why Nurse Doza and many functional practitioners prefer this route.
Glutathione isn't just a detox tool — it's a performance tool. Higher glutathione levels are clinically linked to better energy, sharper cognition, faster recovery, and lower systemic inflammation. That's why it's a cornerstone ingredient in Nurse Doza's practice.
Resources
"Changes in Glutathione Content in Liver Diseases: An Update" — Peer-reviewed review (Antioxidants, 2021) confirming that glutathione is particularly concentrated in the liver and is central to redox balance, detoxification, and the pathogenesis of liver disease.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7997318/
"Glutathione Synthesis in the Mouse Liver Supports Lipid Abundance Through NRF2 Repression" — Nature Communications (2024) research showing glutathione levels are highest in liver tissue and that hepatic GSH synthesis is essential to systemic redox buffering.
https://www.nature.com/articles/s41467-024-50454-2
"Global Incidence and Prevalence of Nonalcoholic Fatty Liver Disease" — PMC systematic review estimating global adult NAFLD prevalence at 32%, with rates exceeding 40% in the Americas — directly relevant to the episode's discussion of compromised glutathione production.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10029957/
"Glutathione in the Treatment of Liver Diseases: Insights from Clinical Practice" — PubMed-indexed clinical review (Free Radical Biology and Medicine) on how GSH administration supports recovery from oxidative stress-induced liver damage in both alcoholic and non-alcoholic liver disease.
https://pubmed.ncbi.nlm.nih.gov/27603810/
"Alterations in Glutathione Redox Homeostasis in Metabolic Dysfunction-Associated Fatty Liver Disease" — Systematic review (Antioxidants, 2024) confirming that the liver is central for glutathione production and that redox imbalances drive multi-organ damage.
https://www.mdpi.com/2076-3921/13/12/1461
Connect with Nurse Doza
🔗 JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza
Monday Apr 20, 2026
Monday Apr 20, 2026
A look into a School of Doza — Lunch & Learn Session
🍽️ What Is a Lunch & Learn?
Lunch & Learns are live health education sessions hosted by Nurse Doza, held twice a month on YouTube and Facebook. Each session dives deep into a real health topic — no fluff, just practical, research-backed information you can use the same day.
Sessions are announced by scheduling them on YouTube. Subscribe and hit the notification bell so you never miss a live session — that's the only way to get notified when the next one drops.
👉 Subscribe here: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Fatty liver affects 1 in 4 adults worldwide, yet most people don't know they have it. In this Lunch & Learn session, Nurse Doza breaks down what fatty liver is, what's causing it—from fast food and sodas to medications and food additives—and 5 practical steps you can take to start improving your fatty liver today.
Liver Boost by MSW Nutrition
Liver Boost is a 16-ingredient formula specifically chosen to support liver detoxification, reduce inflammation, and help reverse the damage caused by the everyday foods and habits discussed in this session.
👉 Get Liver Boost here: https://mswnutrition.com/products/liver-boost
5 KEY TAKEAWAYS
Fatty liver is more common than you think. One in four adults worldwide has fatty liver—caused not just by alcohol, but by fast food, sodas, medications, food dyes, and processed ingredients.
Fatty liver comes before weight gain. Most people assume being overweight causes fatty liver, but it's the other way around—fatty liver develops first, setting the stage for insulin resistance, obesity, and metabolic disease.
Diet sodas are not a safe alternative. Aspartame and other artificial sweeteners can't be processed by the body for energy, so they get stored in the liver as plaque—the same advanced glycated end products (AGEs) linked to Alzheimer's and dementia.
The liver stores everything you eat. Food is processed through the gut, metabolized, and deposited in the liver first—before muscles and fat cells. Every cheeseburger, tortilla, creamer, and soda makes a deposit. The liver is like a refrigerator that never gets cleaned.
You can support and reverse fatty liver. Real food, movement after meals, and targeted supplements like Liver Boost (containing milk thistle, NAC, turmeric, broccoli extract, and more) can help reduce liver inflammation and support detoxification.
TIMESTAMPS
00:00 – START
02:00 – What makes the liver unique and why it's so vulnerable
03:30 – How medications, alcohol, and food cause liver damage
05:00 – Fast food and fatty liver
08:00 – How the liver processes hormones
10:30 – The liver as a refrigerator
12:30 – Diet sodas, aspartame, and the link to fatty liver and dementia
17:00 – AGEs and Alzheimer's disease
20:00 – What fatty liver looks like at breakfast
23:00 – The first symptom of fatty liver and the chicken-or-egg question
25:00 – How food is stored
28:00 – Insulin resistance, fat cells, and visceral fat explained
31:00 – Food industry failures
34:00 – 5 steps to improve fatty liver and why diet change must come first
39:00 – Final thoughts and closing
RESOURCES
Fatty liver disease prevalence and global statistics — https://www.who.int/news-room/fact-sheets/detail/hepatitis
Non-alcoholic fatty liver disease (NAFLD) overview — https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567
Acetaminophen and liver damage — https://www.fda.gov/drugs/medication-health-fraud/acetaminophen-information
Statins and liver toxicity — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716701/
Oral contraceptives and gallbladder/gallstone risk — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976518/
High fructose corn syrup and fatty liver — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443598/
Aspartame, neurological effects, and metabolic impact — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450819/
Advanced glycated end products (AGEs) and Alzheimer's disease — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712798/
Diet soda consumption and dementia risk — https://www.ahajournals.org/doi/10.1161/STROKEAHA.116.016027
Black coffee and fatty liver reversal — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862107/
Walking after meals and blood sugar regulation — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240991/
Gut microbiome disruption and fatty liver disease — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140150/
Milk thistle (silymarin) and liver protection — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408678/
NAC and alpha-lipoic acid in liver support — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533395/
CONNECT
YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
Instagram: https://www.instagram.com/nursedoza/
Website: http://www.nursedoza.com/
LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
TikTok: https://www.tiktok.com/@nursedoza
Twitter: https://twitter.com/nursedoza
Friday Apr 17, 2026
Friday Apr 17, 2026
On this Wellness Tech Series episode, Nurse Doza breaks down why red light therapy has become his go-to biohacking tool for mitochondrial health. He reviews the handheld LightpathLED panel he travels with — a dual-mode device combining red and blue light to regenerate cells, support skin health, and combat the effects of low solar exposure. Easy to use, easy to charge, and powerful enough to deliver results in just 10 minutes a day.
Featured Partner: LightpathLED
LightpathLED builds professional-grade red light therapy panels engineered for at-home and travel use — including compact handheld combo devices that deliver red (670 nm) and blue (450 nm) wavelengths in a single unit. That dual-mode technology directly addresses the two benefits Nurse Doza highlights in this episode: mitochondrial regeneration through red light and skin clarity through blue light. With the industry's densest LED count per square inch and a 5-year warranty, it's the red light panel built for people who are serious about their mitochondrial health.
👉 Get your LightpathLED red light panel here: https://lightpathled.com/
👉 Use code NURSEDOZA at
5 Key Takeaways
Red light regenerates your mitochondria. Red and near-infrared light in the 600–1000 nm range is absorbed by cytochrome c oxidase in the mitochondrial electron transport chain, increasing ATP production and cellular energy. This is the foundational mechanism that makes red light therapy powerful for whole-body recovery.
Most of us are solar-starved. Indoor living, screens, and chronic stress leave most people deficient in the red-spectrum light their cells need to function. A handheld red light panel isn't a replacement for sunlight — but it's the next best thing for daily cellular maintenance.
There's serious mitochondrial density in your eyes and brain. Red and near-infrared wavelengths in the 600–1000 nm range can penetrate bone to reach brain tissue, supporting cognitive function and visual health — two areas where mitochondrial support matters most as we age.
Blue light mode handles skin and acne. The LightpathLED combo panel pairs red light with ~450 nm blue light, which targets oil production and acne-causing bacteria. Around 10 minutes a day can deliver measurable skin improvements in weeks.
10 minutes a day is the game-changer. You don't need a full biohacking clinic. A handheld panel used once daily — morning is ideal — compounds into significant cellular, skin, and mood benefits over a few months. Consistency beats intensity.
Resources
"Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation" — PMC review detailing how red and near-infrared light is absorbed by cytochrome c oxidase in mitochondria, increasing ATP production and triggering beneficial redox signaling.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5844808/
"Light stimulation of mitochondria reduces blood glucose levels" — Journal of Biophotonics 2024 study showing a 15-minute exposure to 670 nm red light reduced post-meal blood glucose elevation by 27.7% — direct evidence that photobiomodulation improves metabolic function.
https://pubmed.ncbi.nlm.nih.gov/38378043/
"From Light to Healing: Photobiomodulation Therapy in Medical Disciplines" — 2024 systematic review in PMC covering PBM's evolution from an adjunctive therapy to an evidence-based modality influencing mitochondrial bioenergetics, neuroplasticity, and tissue regeneration across dermatology, musculoskeletal, and neurological applications.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12751248/
"Visible Light in the Treatment of Acne Vulgaris" — 2024 systematic review of 35 studies and 1,185 acne cases finding 92% of patients achieved partial remission of acne lesions using visible light therapy, with blue light being the most effective modality.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11585190/
"Effect of Red Light on Epidermal Proliferation and Mitochondrial Activity" — PMC study demonstrating that 630 nm red light increases both epidermal cell proliferation and mitochondrial activity in human skin, supporting red light's role in skin health and regeneration.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10462800/
Monday Apr 13, 2026
Monday Apr 13, 2026
Fatty liver and insulin resistance form a dangerous loop driving diabetes, dementia, and colon cancer. Learn what causes this cycle, what happens when it keeps running, and how diet, fasting, the Mediterranean diet, and targeted supplements can break it for good.
FEATURED PRODUCT
The Good Poops Protocol — combining Liver Boost, Gut Powder, and Berberine Plus — directly targets both sides of the fatty liver and insulin resistance loop discussed in this episode. Liver Boost supports your liver's ability to process fats and manage detoxification, Berberine Plus has been shown to improve insulin sensitivity and lower pro-inflammatory cytokines, and Gut Powder addresses the digestive consequences — bloating, constipation, and gut dysfunction — that compound when this loop goes unchecked. Together, these three work on the liver, the blood sugar, and the gut simultaneously, which is exactly what this episode makes clear you need.
👉 Get the Good Poops Protocol here: https://goodpoops.org
JOIN THE SCHOOL
If this episode hit home — if you recognized yourself in the fatty liver, high insulin, or gut dysfunction piece — the School of Doza is exactly where you need to be. Every Wednesday we host a live one-hour Ask Me Anything that functions like a group consult. Bring your labs, your diet questions, your supplement stack, your specific symptoms — and get direct guidance in real time. You're not doing this alone. There's an entire community of people working through the same metabolic challenges, and you can be part of it starting today. Your first seven days are completely free.
👉 Start your free trial: https://community.schoolofdoza.com/c/start-here
5 KEY TAKEAWAYS
- Fatty liver and insulin resistance are a two-way loop. The liver helps regulate insulin, and insulin helps regulate the liver — meaning if one is dysfunctional, the other follows. You can't fix one without addressing the other.
- Diet is both the cause and the cure. Bread, rice, pasta, processed foods, and excess sugar drive fatty liver and high insulin. Fasting and the Mediterranean diet are backed by research to reverse both conditions — no medication required.
- The consequences go far beyond the liver. This loop is directly linked to colon cancer, dementia (type 3 diabetes), chronic fatigue, and severe digestive dysfunction. Ignoring it doesn't keep it contained — it spreads.
- Adiponectin and leptin are the hormones most doctors aren't checking. Low adiponectin and high leptin are associated with fatty liver, insulin resistance, colorectal cancer, and dementia. Along with insulin and GGT, these are the four labs you need to be tracking.
- Berberine is one of the most research-supported supplements for breaking this loop. It lowers insulin, reduces pro-inflammatory cytokines (TNF-α and IL-6), and has been shown to increase adiponectin — directly targeting the metabolic dysfunction driving this cycle.
TIMESTAMPS
00:00 – START – Welcome and episode overview
01:20 – The fatty liver and insulin resistance connection explained
03:00 – School of Doza AMA and free trial offer
04:10 – What's causing the loop: diet, bread, rice, and pasta
06:30 – How the liver processes insulin and why fatty liver means liver-based insulin resistance
08:00 – Generational diet trauma and the 15-year slow burn to fatty liver
10:20 – Advanced glycation end products, plaque, and the brain connection
12:30 – The inflammation loop: how a fatty liver loses its ability to make antioxidants
14:50 – Digestive consequences: bloating, constipation, SIBO, and gut dysfunction
16:30 – Colon cancer, colorectal risk, and the fatty liver link
18:50 – Adiponectin: the anti-inflammatory hormone no one is testing
21:30 – Leptin, carcinogenesis, and how fat cells regulate inflammation
24:00 – Labs to order: insulin, adiponectin, leptin, and GGT
27:00 – Solutions: fasting, Mediterranean diet, and resistance training
29:00 – Supplements: Berberine Plus, Liver Boost, and the Good Poops Protocol
31:00 – Closing: take action, share the episode, and join the School
RESOURCES
- Pathophysiology of NAFLD — insulin resistance, obesity, and steatosis as precursor stages. https://pmc.ncbi.nlm.nih.gov/articles/PMC10638269/
- The liver's role in glucose homeostasis and insulin degradation via insulinase and IDE. https://pmc.ncbi.nlm.nih.gov/articles/PMC11850106/
- Peripheral insulin resistance, IDE activation, and advanced glycation end product accumulation. https://pmc.ncbi.nlm.nih.gov/articles/PMC8472298/
- Adiponectin, NAFLD, and colorectal cancer risk — adiponectin deficiency, leptin-driven carcinogenesis, and HbA1c above 7% increasing colorectal cancer risk by 33% per 1% increase. https://pmc.ncbi.nlm.nih.gov/articles/PMC3523590/
- NAFLD, dementia, and cognitive impairment — insulin resistance, hyperammonemia, gut microbiota disruption, and inflammation as neurological drivers. https://pubmed.ncbi.nlm.nih.gov/35831178/
- Alternate-day fasting and fatty liver disease — improved insulin sensitivity, reduced liver fat, and lower ALT markers over three months. https://today.uic.edu/alternate-day-fasting-a-good-option-for-patients-with-fatty-liver-disease/
- Mediterranean diet, cardiovascular disease, metabolic syndrome, and type 2 diabetes — antioxidants, fiber, MUFA, and omega-3 balance. https://pmc.ncbi.nlm.nih.gov/articles/PMC5960814/
- Mediterranean diet reducing liver steatosis and improving insulin sensitivity in NAFLD without weight loss. https://www.sciencedirect.com/science/article/abs/pii/S0168827813001347
- Resistance training and liver lipid reduction — 13% relative reduction in liver lipid, improved glucose control and insulin resistance. https://gut.bmj.com/content/60/9/1278
- Berberine's role in treating NAFLD, obesity, and diabetes — LDLR, AMPK, and PPAR molecular targets. https://pmc.ncbi.nlm.nih.gov/articles/PMC12833932/
CONNECT
🔗 Connect with Nurse Doza: JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/start-here
- YouTube: https://www.youtube.com/channel/UCwcKyagDi468WscAOWM5VHA
- Instagram: https://www.instagram.com/nursedoza/
- Website: http://www.nursedoza.com/
- LinkedIn: https://www.linkedin.com/in/jonathan-mendoza-dc-aprn-np-c-0609a038/
- TikTok: https://www.tiktok.com/@nursedoza
- Twitter: https://twitter.com/nursedoza
Thursday Apr 09, 2026
Thursday Apr 09, 2026
Feeling drained, foggy, and inflamed — and can't figure out why? In this episode of the supplement ingredient series, Nurse Doza breaks down glutathione, the body's master antioxidant. Produced in the liver and essential for fighting oxidative stress, glutathione levels are depleted in 1 in 4 people with fatty liver — making supplementation a game-changer for energy, brain clarity, digestion, and overall detox capacity.
Featured Partner: SHED
SHED delivers glutathione in a direct-to-bloodstream vial format — bypassing the gut degradation that makes most oral supplements ineffective. For anyone battling fatty liver, brain fog, low energy, or chronic inflammation (exactly the conditions discussed in this episode), SHED's bioavailable glutathione offers what diet alone can't replicate: fast, measurable antioxidant replenishment at the cellular level.
👉 Get SHED Glutathione — Use Code DOZA30
Use code DOZA30 at: https://tryshed.com
Join the School of Doza
If this episode hit home — if you're running low on energy, dealing with stubborn brain fog, or wondering why your body can't seem to keep up — the School of Doza was built for you. Inside, you'll join a community of people asking the same hard questions and finally getting real answers from a functional practitioner who connects the dots.
Every Wednesday at 1 PM Central, Nurse Doza hosts a live ask me anything group consult. Bring your labs, your supplement questions, your inflammation frustrations. Topics like glutathione depletion, liver health, gut-brain connection, hormones, and autoimmune dysfunction are all fair game. Some students ask questions, some just listen and learn — either way, you leave with clarity.
Not sure yet? Try it completely FREE for one week. Get inside, attend a Wednesday class, and see if this is the missing piece.
👉 Start your free trial: https://community.schoolofdoza.com/c/start-here
5 Key Takeaways
- Glutathione is the body's master antioxidant — and most people are running low. Your liver produces it, but chronic stress, poor diet, and fatty liver disease rapidly deplete it. Low glutathione means your cells can't neutralize oxidative damage fast enough — and you feel it.
- 1 in 4 people worldwide have fatty liver — and fatty liver tanks glutathione. When liver function is compromised, your body's capacity to produce and recycle glutathione drops significantly, creating a cascade of systemic inflammation and oxidative stress.
- Supplementing glutathione can produce noticeable results fast. Patients commonly report better energy, reduced brain fog, improved digestion, and better gut motility within a short period of starting glutathione supplementation — because it addresses the root cause rather than just the symptoms.
- Brain fog isn't just mental — it's biochemical. Research links glutathione depletion in the brain to reduced memory, cognitive decline, and neuroinflammation. Restoring glutathione levels can improve mental clarity and neuroprotection.
- Delivery method matters. Standard oral glutathione is broken down in the gut before it reaches your cells. Bioavailable formats — like SHED's vial delivery — are designed to improve absorption and maximize the antioxidant benefit where it counts.
Resources
- "Glutathione Therapy in Non-Alcoholic Fatty Liver Disease" — 2025 literature review from PMC/PubMed examining glutathione supplementation in NAFLD patients across RCTs from 2014–2024, demonstrating promising potential for reducing oxidative stress, maintaining redox balance, and improving liver function.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11940638/
- "Efficacy of Glutathione for the Treatment of Nonalcoholic Fatty Liver Disease" — Open-label multicenter pilot study from PMC/NIH demonstrating that oral glutathione supplementation significantly reduced ALT levels in NAFLD patients, with measurable improvements in liver fat and oxidative stress markers.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5549431/
- "Glutathione: Pharmacological Aspects and Implications for Clinical Use in NAFLD" — Frontiers in Medicine (2023) comprehensive review of glutathione's role in cellular detoxification, phase I and II liver metabolism, immune modulation, and its therapeutic potential in fatty liver disease.
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1124275/full
- "Glutathione in the Brain — NIH/PMC" — NIH review examining glutathione's central role in neuroprotection, brain antioxidant defense, and how GSH depletion is a common finding in cognitive decline, neurodegeneration, and brain fog conditions.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8125908/
- "Alterations in Glutathione Redox Homeostasis in Metabolic Dysfunction-Associated Fatty Liver Disease" — 2024 systematic review (Antioxidants) analyzing 165 eligible studies on the relationship between low-molecular-weight thiols — especially glutathione — and the severity of fatty liver disease in humans.